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Reference sheet · Antimicrobial · CPC catalog code DEFS-007
Composition figures above are derived arithmetically from the published sequence for the unmodified free peptide. Salt forms (commonly trifluoroacetate or acetate), amidation, and other modifications shift the observed mass — always reconcile against the current lot certificate of analysis.
Volumes for a 1 mg vial of Defensin HNP-3 (human) at common working concentrations. Add solvent slowly down the vial wall and swirl — do not vortex or shake.
Reference standards in the Antimicrobial class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.
Defensin HNP-3 (human) sits within the Antimicrobial research class (CPC reference DEFS-007). Antimicrobial peptides typically disrupt bacterial, fungal, or viral membranes through direct electrostatic and hydrophobic interactions, or by triggering intracellular targets after translocation. Assay potency is usually reported as MIC (minimum inhibitory concentration) against reference strains. Investigators typically incorporate Defensin HNP-3 (human) as a reference standard, tool ligand, or substrate in the assay contexts listed above. Most commonly used in broth microdilution MIC assays (CLSI M07), radial diffusion assays, and membrane-permeabilization (SYTOX / DiSC₃-5) readouts.
Defensin HNP-3 (human) (CPC catalog code DEFS-007) is a synthetic antimicrobial peptide (amp) reference standard in the antimicrobial category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.
Published and internal research programs use Defensin HNP-3 (human) as a reference standard in antimicrobial workflows — for example, minimum inhibitory concentration (mic) screens against gram-positive and gram-negative panels and biofilm disruption and anti-biofilm surface coatings. Human clinical evidence is not established.
No. Defensin HNP-3 (human) is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.
In a antimicrobial workflow, Defensin HNP-3 (human) is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Most commonly used in broth microdilution MIC assays (CLSI M07), radial diffusion assays, and membrane-permeabilization (SYTOX / DiSC₃-5) readouts.
Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.