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Peptides shop · Mast Cell Degranulating Peptide HR-1 · Reference sheet

Mast Cell Degranulating Peptide HR-1

Reference sheet · Antimicrobial · CPC catalog code MCDP-001

Identity

Name
Mast Cell Degranulating Peptide HR-1
Catalog code
MCDP-001
Category
Antimicrobial

Physicochemical properties

Sequence
H-Ile-Asn-Leu-Lys-Ala-Ile-Ala-Ala-Leu-Val-Lys-Lys-Val-Leu-NH2 (trifluoroacetate salt)
One-letter
INLKAIAALVKKVL
Residues
14 amino acids
Modifications
NH2
Net charge (pH 7)
+3 (3 basic / 0 acidic)
Hydrophobic residues
71%
Cysteine present
No

This sequence carries terminal or reporter modifications (NH2), so no molecular formula or weight is published here — the modified mass must come from the lot certificate of analysis. Residue composition and charge describe the peptide backbone only. Composition figures above are derived arithmetically from the published sequence for the unmodified free peptide. Salt forms (commonly trifluoroacetate or acetate), amidation, and other modifications shift the observed mass — always reconcile against the current lot certificate of analysis.

Reconstitution reference

Volumes for a 1 mg vial of Mast Cell Degranulating Peptide HR-1 at common working concentrations. Add solvent slowly down the vial wall and swirl — do not vortex or shake.

10 mg/mL
0.1 mL diluent per 1 mg
5 mg/mL
0.2 mL diluent per 1 mg
2 mg/mL
0.5 mL diluent per 1 mg
1 mg/mL
1 mL diluent per 1 mg

Handling, storage & reconstitution

Upstream storage
-20 ± 5 °C

General guidance for this class

Reference standards in the Antimicrobial class are typically shipped as lyophilized powder and stored desiccated at −20 °C protected from light. Once reconstituted in bacteriostatic water or the assay-appropriate buffer, aliquot and store at −80 °C to minimize freeze–thaw cycles. Confirm handling requirements against your institutional biosafety and radiation protocols before use.

Mechanism & research applications

Mast Cell Degranulating Peptide HR-1 sits within the Antimicrobial research class (CPC reference MCDP-001). Antimicrobial peptides typically disrupt bacterial, fungal, or viral membranes through direct electrostatic and hydrophobic interactions, or by triggering intracellular targets after translocation. Assay potency is usually reported as MIC (minimum inhibitory concentration) against reference strains. Investigators typically incorporate Mast Cell Degranulating Peptide HR-1 as a reference standard, tool ligand, or substrate in the assay contexts listed above. Most commonly used in broth microdilution MIC assays (CLSI M07), radial diffusion assays, and membrane-permeabilization (SYTOX / DiSC₃-5) readouts.

Studied for

  • Minimum inhibitory concentration (MIC) screens against Gram-positive and Gram-negative panels
  • Biofilm disruption and anti-biofilm surface coatings
  • Structure–activity relationship (SAR) studies for AMP analogues
  • Host-defense and innate-immunity mechanistic work

Frequently asked

What is Mast Cell Degranulating Peptide HR-1?

Mast Cell Degranulating Peptide HR-1 (CPC catalog code MCDP-001) is a synthetic antimicrobial peptide (amp) reference standard in the antimicrobial category. It is provided as a lyophilized ~1 mg vial for in-vitro research use only.

What is Mast Cell Degranulating Peptide HR-1 studied for?

Published and internal research programs use Mast Cell Degranulating Peptide HR-1 as a reference standard in antimicrobial workflows — for example, minimum inhibitory concentration (mic) screens against gram-positive and gram-negative panels and biofilm disruption and anti-biofilm surface coatings. Human clinical evidence is not established.

Is Mast Cell Degranulating Peptide HR-1 FDA-approved for human use?

No. Mast Cell Degranulating Peptide HR-1 is a research-grade reference peptide and is not approved by the FDA or any national regulator for human or veterinary therapeutic use. It is offered exclusively for in-vitro laboratory research and does not ship to the United States for consumer use.

How is Mast Cell Degranulating Peptide HR-1 typically used in the lab?

In a antimicrobial workflow, Mast Cell Degranulating Peptide HR-1 is reconstituted in sterile buffer or DMSO (solubility-dependent) and applied in the researcher's chosen assay format. Most commonly used in broth microdilution MIC assays (CLSI M07), radial diffusion assays, and membrane-permeabilization (SYTOX / DiSC₃-5) readouts.

Sources

View full product page →Back to catalog

Related peptides in Antimicrobial

Other reference standards in the same class — commonly cross-referenced during assay design and comparator selection.

Mast Cell Degranulating Peptide HR-2
Mast Cell Degranulating Peptide
alpha-Bag Cell Peptide (1-7)
alpha-Bag Cell Peptide (1-8)
alpha-Bag Cell Peptide (1-9)
gamma-Bag Cell Factor
beta-Bag Cell Factor
Lactoferricin, bovine, (BLFC)
Research use only. The peptides referenced on this page are supplied to qualified laboratories for in-vitro or non-human research. They are not drugs, foods, cosmetics, or dietary supplements, are not for human consumption, and are not intended to diagnose, treat, cure, or prevent any disease. Physicochemical values shown here are transcribed from the cited upstream reference sheet(s); confirm with your own certificate of analysis before use.